Dennis M Lox
Sports and Regenerative Medicine Centers, USA
Title: Bio-scaffolds and stem cells in knees
Biography
Biography: Dennis M Lox
Abstract
The use of various scaffolds, matrix materials, and stem cells in regenerative medicine and tissue engineering has proliferated in the last decade. The inter-lapping nature of regenerative medicine and tissue engineering, has explored the fundamentals of bioscience, cellular signaling, and aging. The various engineered scaffolds have included synthetic, allogenic, autologous, xenographic, natural matrix substrates and 3-D bio-printing. Cellular medicine has also explored various types of cells including autologous, allogenic, and perinatal. The animal model has yielded promising results, yet a fundamental difference in human diverse behavior and inter-patient variability, may ultimately prove impossible to extrapolate from more simplistic animal model studies. The inherent nature of degenerative osteoarthritis of the knee is a progressive phenomenon. The role of cellular medicine and bio-scaffolds may alter the nature of osteoarthritis over time, thus impacting functional level and quality of life (QoL). The future of improving quality of life (QoL) may find a common thread in preventative and regeneration medicine.