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Theme: Addressing New Challenges and Emerging Issues in Bioscience

Bioscience 2017

scientific Program 2017

Renowned Speakers

Alan M Hoberman
Charles River Laboratories
USA

Antonia dos Reis Figueira
Universidade Federal de Lavras
Brazil

Basak Kusakci Seker
Eskisehir Osmangazi University
Turkey

Antonia Tamborrino
University of Bari Aldo Moro
Italy

Alessandro Leone
University of Foggia
Italy

Esma Eryilmaz
Selcuk University
Turkey

Rinku Majumder
LSU Health Science Center
USA

Michael K E Schaefer
Johannes Gutenberg University of Mainz
Germany

Alan R Criollo RÃ³diz
Kabla Diagnostics
Mexico

Hiroyuki Akazawa
Nihon University Junior College
Japan

Roberto Romaniello
University of Foggia
Italy

Hanieh Yazdanfar
University of Leicester
UK

Bioscience 2017

Bioscience International Conferences invites all the participants from all over the world to attend 2^nd International Conference on Bioscience during June 19-20, 2017 in London, UK which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions.

Bioscience is defined as technologies that relate to therapeutic or diagnostic products or services, including medical devices and digital health technologies that improve human health. Also included in the state definition are technologies that rely on research to improve agricultural output. As name “Bioscience” reflects belief that the study of biological systems is best approached by incorporating many perspectives. We bring together a diversity of disciplines that complement one another to unravel the complexity of biology. We incorporate the physical sciences, engineering, mathematics, computational and bioinformatics, and the social sciences, as appropriate, to problems we are addressing. We work with animals, plants and microorganisms and our research spans the levels of the biological hierarchy from molecules to ecosystems.

Bioscience International organizes a conference series of 1000+ Global Events inclusive of 300+ Conferences, 500+ Upcoming and Previous Symposiums and Workshops in USA, Europe & Asia with support from 1000 more scientific societies and publishes 700+ Open access journals which contains over 30000 eminent personalities, reputed scientists as editorial board members.

Why to attend???

This unique international conference provides a platform for researchers and decision makers in Bioscience to present their latest findings and learn about all the important developments in bioscience. Many scientists and world's renowned experts will participate in the conference. Throughout the course of the two day conference, you will have the opportunity to both network and hear leaders from the international academic and corporate bioscience communities.

Target Audience:

The conference will attract a large group of scientists and researchers from round the globe. Delegates will have a valuable, informative and positive experience.

Biotechnologists
Pharmaceutical Experts
CEOs, CROs, directors and research associates from the bioscience industries
Young Scientists
Academic Students
Bioscience Faculty
Bioscience Counselors
Business Entrepreneurs

Bioscience: It is defined as technologies that relate to therapeutic or diagnostic products or services, including medical devices and digital health technologies that improve human health. Also included in the state definition are technologies that rely on research to improve agricultural output. As name “Bioscience” reflects belief that the study of biological systems is best approached by incorporating many perspectives. We bring together a diversity of disciplines that complement one another to unravel the complexity of biology. We incorporate the physical sciences, engineering, mathematics, computational and bioinformatics, and the social sciences, as appropriate, to problems we are addressing. We work with animals, plants and microorganisms and our research spans the levels of the biological hierarchy from molecules to ecosystems.

Agriculture Bioscience:- Agriculture is the systematic raising of useful plants and livestock under the management of man. Agricultural Activity means the cultivation of the soil, planting of crops, growing of fruit trees, including the harvesting of such farm products, and other farm activities and practices performed by a farmer in conjunction with such farming operations done by persons whether natural or juridical. The practice of agriculture is based on systematized body of knowledge (science) and requires skill (art).

Biochemical Engineering:- Biochemical engineers translate exciting discoveries in life sciences into practical materials and processes contributing to human health and well-being.biochemical engineering is mainly deals with the design and construction of unit processes that involve biological organisms or molecules, such as bioreactors. Its applications are in the petrochemical industry, food, pharmaceutical, biotechnology, and water treatment industries.

Biomaterials and Materials science:- A biomaterial is any substance that has been built to cooperate with natural frameworks for a restorative reason - either a remedial or a symptomatic one. As a science, biomaterials are around fifty years of age. The interdisciplinary field of materials science, likewise normally named materials science and building, includes the revelation and outline of new materials, with an accentuation on solids. Materials science is a syncretic train hybridizing metallurgy, pottery, strong state physical science, and science. It is the principal case of another scholastic train developing by combination as opposed to parting.

Biomedical Science:- study human diseases in order to improve human health and Investigations carried out by biomedical scientists on body fluids and samples of tissue to identify the nature of the medical condition of disease and monitor the treatment of patients. The branches of medical science that deal with nonsurgical techniques, studies the causes and nature and effects of diseases and dealing with the medical use of X-rays or other penetrating radiation and nervous system.

Biopharmaceutics and Biochemistry:- Biopharmaceutics is the study which shows how the drug absorption rate is affected by various factors like physical and chemical properties of the drug, the dose form of the drug and the route through which the drug is administered. Drugs are substances intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease. Drugs are given in a variety of dosage forms or drug products such as solids (tablets, capsules), semisolids (ointments, creams), liquids, suspensions, emulsions, etc, for systemic or local therapeutic activity. Drug products can be considered to be drug delivery systems that release and deliver drug to the site of action such that they produce the desired therapeutic effect and are also designed specifically to meet the patient's needs including palatability, convenience, and safety.Medical biotechnology is the use of living cells and cell materials to research and produce pharmaceutical and diagnostic products that help treat and prevent human diseases. Most medical biotechnologists work in academic or industrial settings. In academic laboratories, these professionals conduct experiments as part of medical research studies.

Related Conferences: 3rd International Conference on Systems and Synthetic Biology July 20-21, 2017 Munich, Germany; 7th International Conference on Plant Genomics July 03-05, 2017 Bangkok, Thailand; 8th World Congress and Expo on Cell & Stem Cell Research March 20-22, 2017 Orlando, Florida, USA ; 9th Annual Conference on Stem Cell and Regenerative Medicine Sep 05-06, 2017 Paris, France; 5th International Conference on Integrative Biology June 19-21, 2017 London, UK;

Bioprocess and Biological Engineering:-Bioprocess engineering is the alteration or application of renewable materials to generate value-added products. It encompasses discovery, research, development and the manufacturing and commercialization of products. Products developed include: fuels, food, feed, pharmaceuticals, nutraceuticals and a multitude of value-added biomaterials found in and used by all industries.

Cell Biology: Cell biology clarifies the structure, association of the organelles they contain, their physiological properties, metabolic procedures, flagging pathways, life cycle, and collaborations with their surroundings. This is done both on a minuscule and sub-atomic level as it includes prokaryotic cells and eukaryotic cells. Knowing the segments of cells and how cells function is central to every single organic science; it is additionally key for research in bio-restorative fields, for example, growth, and different illnesses. Explore in cell science is firmly identified with hereditary qualities, natural chemistry, atomic science, immunology, and formative science. Cell science concentrates more on the investigation of eukaryotic cells, and their flagging pathways, as opposed to on prokaryotes which is secured under microbiology. The primary constituents of the general atomic piece of the cell incorporates: proteins and lipids which are either free streaming or film bound, alongside various interior compartments known as organelles.

Cell-Based Therapies:-Cell therapy can be characterized as treatment in which cell material is infused into a patient. There are two branches of cell treatment: one is true blue and set up, whereby human cells are transplanted from a contributor to a patient; the other is hazardous option pharmaceutical, whereby infused creature cells are utilized to endeavor to treat disease.

Drug Discovery and Delivery:-Drug delivery refers to methodologies, definitions, advancements, and frameworks for transporting a pharmaceutical compound in the body as expected to securely accomplish its wanted helpful impact. It might include logical site-focusing inside the body, or it may include encouraging systemic pharmacokinetics.

Food Science:- Food science draws from many disciplines such as biology, chemical engineering, and biochemistry in an attempt to better understand food processes and ultimately improve food products for the general public. As the stewards of the field, food scientists study the physical, microbiological, and chemical makeup of food. By applying their findings, they are responsible for developing the safe, nutritious foods and innovative packaging that line supermarket shelves everywhere.Academic Performance (85% of Admission Score): Admission to the Food Science major is based on a minimum academic standing of 70%, calculated based on the best 21 credits per year of post-secondary courses required in this program. The student must have completed ENGL 112 or equivalent. Elective courses and LFS 100, LFS 250, LFS 350, or LFS 450 are not included in this calculation.

Genomics and Proteomics:-After genomics and proteomics is the following stride in the investigation of natural frameworks. It is more entangled than genomics in light of the fact that a living being's genome is pretty much steady, while the proteome contrasts from cell to cell and every once in a while. Unmistakable qualities are communicated in various cell sorts, which imply that even the fundamental arrangement of proteins that are delivered in a cell should be distinguished.

Genetics:-Genetics is the investigation of single qualities and their part in the way attributes or conditions are passed starting with one era then onto the next. Genetics is the study of genes, genetic variation, and heredity in living creatures. It is by and large considered a field of science, however it converges as often as possible with a significant number of the life sciences and is firmly connected with the investigation of data frameworks.

Immunology and Inflammation:-Immunology is a branch of science that covers the investigation of invulnerable frameworks in all life forms. It concentrates the relationship between the body frameworks, pathogens, and insusceptibility. The investigation of the atomic and cell parts that involve the safe framework, including their capacity and connection, is the focal art of immunology. Aggravation is a piece of the complex organic reaction of body tissues to hurtful jolts, for example, pathogens, harmed cells, or aggravations, and is a defensive reaction including insusceptible cells, veins, and sub-atomic go between. The capacity of irritation is to dispose of the underlying reason for cell harm, get out necrotic cells and tissues harmed from the first affront and the fiery procedure, and to start tissue repair.

Microbial Pathogenicity:-Pathogenic microscopic organisms are microbes that can bring about disease. Every species has particular impact and causes side effects in individuals who are contaminated. A few, if not a great many people who are contaminated with a pathogenic microscopic organisms don't have manifestations. Immune-bargained people are more defenceless to pathogenic microbes.

Microbiology:- Microbiology is the study of microscopic organisms, such as bacteria, viruses, archaea, fungi and protozoa. This discipline includes fundamental research on the biochemistry, physiology, cell biology, ecology, evolution and clinical aspects of microorganisms, including the host response to these agents. Microorganisms are beneficial for microbial biodegradation or bioremediation of domestic, agricultural and industrial wastes and subsurface pollution in soils, sediments and marine environments. The ability of each microorganism to degrade toxic waste depends on the nature of each contaminant.Symbiotic microbial communities are known to confer various benefits to their human and animal hosts health including aiding digestion, production of beneficial vitamins and amino acids, and suppression of pathogenic microbes. Some benefit may be conferred by consuming fermented foods, probiotics or prebiotics . The ways the microbiome influences human and animal health, as well as methods to influence the microbiome are active areas of research.Research has suggested that microorganisms could be useful in the treatment of cancer. Various strains of non-pathogenic clostridia can infiltrate and replicate within solid tumors. Clostridial vectors can be safely administered and their potential to deliver therapeutic proteins has been demonstrated in a variety of preclinical models.

Molecular Biology:- Molecular Biology covers a wide scope of problems related to molecular and cell biology including structural and functional genomics, transcriptomics, proteomics, bioinformatics, biomedicine, molecular enzymology, molecular virology and molecular immunology, theoretical bases of biotechnology, physics and physical chemistry of proteins and nucleic acids. Unlike the majority of journals dealing with these subjects, Molecular Biology exercises a multidisciplinary approach and presents the complete pattern of relevant basic research mostly in Eastern Europe. Molecular Biology publishes general interest reviews, mini-reviews, experimental and theoretical works and computational analyses in molecular and cell biology.The molecular components make up biochemical pathways that provide the cells with energy, facilitate processing “messages” from outside the cell itself, generate new proteins, and replicate the cellular DNA genome. For example, molecular biologists study how proteins interact with RNA during “translation” (the biosynthesis of new proteins), the molecular mechanism behind DNA replication, and how genes are turned on and off, a process called “transcription.”

Molecular Biotechnology:- In its broadest sense, molecular biotechnology is the use of laboratory techniques to study and modify nucleic acids and proteins for applications in areas such as human and animal health, agriculture, and the environment. Molecular biotechnology results from the convergence of many areas of research, such as molecular biology, microbiology, biochemistry, immunology, genetics, and cell biology. It is an exciting field fueled by the ability to transfer genetic information between organisms with the goal of understanding important biological processes or creating a useful product. The completion of the human genome project has opened a myriad of opportunities to create new medicines and treatments, as well as approaches to improve existing medicines. Molecular biotechnology is a rapidly changing and dynamic field. As the pace of advances accelerates, its influence will increase. The importance and impact of molecular biotechnology is being felt across the nation.

Molecular Plant Sciences:-Green plants have cell dividers with cellulose and acquire the greater part of their vitality from daylight by means of photosynthesis by essential chloroplasts, got from endosymbiosis with cyanobacteria. Green plants give the vast majority of the world's atomic oxygen and are the premise of a large portion of Earth's ecologies, particularly ashore.

Nano-Biotechnology:- Nanotechnology is the engineering of functional systems at the molecular scale. This covers both current work and concepts that are more advanced.In its original sense, 'nanotechnology' refers to the projected ability to construct items from the bottom up, using techniques and tools being developed today to make complete, high performance products.

Tissue Engineering & Stem cell research:-Tissue building is the utilization of a mix of cells, designing and materials techniques, and appropriate biochemical and physicochemical elements to enhance or supplant natural tissues. Tissue building includes the utilization of a platform for the development of new feasible tissue for a therapeutic reason. While it was once sorted as a sub-field of biomaterials, having developed in degree and significance it can be considered as a field in its own. Foundational microorganisms are undifferentiated natural cells that can separate into specific cells and can isolate to create more undeveloped cells. They are found in multicellular life forms. In well evolved creatures, there are two expansive sorts of undifferentiated cells: embryonic foundational microorganisms, which are separated from the internal cell mass of blastocysts, and grown-up undeveloped cells, which are found in different tissues. In grown-up living beings, immature microorganisms and begetter cells go about as a repair framework for the body, renewing grown-up tissues.

Source BioScience is an international laboratory services and products business with nine state of the art facilities in five countries and with customers in over 90 countries worldwide. The Group offers a complementary portfolio of services and products that share common technologies, laboratory processes, infrastructure and expertise.

LifeSciences

LifeSciences delivered revenue of £7.2 million (2013: £7.6 million) and a divisional operating profit of £1.1 million (2013: £1.2 million) as the Group invested to extend its market coverage and expand its specialist product offering. Source BioScience’s ambition is to become Europe and the USA’s leading commercial provider of DNA sequencing and the Overnight Service™, which provides rapid access to sequencing data, is instrumental in achieving this. The Group’s market share in the UK continues to increase and DNA sequencing volumes during 2014 were over 30% greater thanthe prior year, driving both revenue and margin growth.

Healthcare

Healthcare revenue increased by 7% to £10.0 million (2013: £9.4 million) and divisional operating profit increased by 15% to £3.4 million (2013: £3.0 million).The diagnostic activities continued the impressive performance reported at the half year and the aggregate number of diagnostic tests conducted increased by over 70% compared with 2013.

Bioscience 2015 was published in 2003. Today, nearly six years later, one is bound to have mixed reactions about what has been achieved by the UK bioscience sector. More worrying are the immediate prospects for what should be one of our high achieving, knowledge based industries. Senior people from Bioscience companies, Government Departments, Trade Associations, universities and research bodies have been involved in the Review and Refresh of Bioscience 2015. This report reflects the broad consensus of their views, through not necessarily those of the Government or Government officials, nor individuals, companies or organisations involved in the process.

A vision for bioscience

Over the five years since Bioscience 2015 was published, UK bioscience companies have struggled to achieve the vision it laid out, while other European companies have caught up with the UK in terms of projects in the pipeline. For example, in 2002 46% of the EU products in clinical trial development were in the UK. By 2007 this had reduced to 24% and analysis of the numbers of UK companies listed since 2002 shows that the number of companies with a market capitalisation of less than £25m has increased (see Market Capitalisation graph Fig 5) while the number of companies with a market capitalisation of more than £25 million has decreased. Therefore, although there may be a similar number of companies there is significantly less investment in those companies, preventing them from growingwhich is contrary to the hopes for the sector held in 2003. Therefore, there is a need for a more realistic vision given what is achievable in the time frame to 2015.

Increasing finance to bioscience SMEs: Government schemes

Government provides a number of schemes to support enterprises and is currently undertaking an exercise to simplify the support available. Businesses in all sectors will benefit from a simplified business support landscape, which will help them access the provision they need more easily. There are particular issues around the high risk of investing in bioscience, which have meant that the sector has not been able to fully benefit from some of the schemes.

In 2014, the European trend lines followed those in the US, albeit the trajectories for each of the key performance metrics did not reach the same heights. European biotech companies saw their revenue growth rebound strongly in 2014, as top-line sales expanded 15%, compared to the modest 3% uptick of 2013. In a sign of a healthier financial picture, 77% of European biotechs generated some revenue and 69% increased their top lines year over year. Those results are comparable to the revenue metrics posted by US biotech companies.

EU Clinical Trials Directive – Directive implemented in 2004 with the aim of patient protection, improved research reporting, harmonisation and increased competitiveness of European clinical research.

As in the US, European biotech companies’ aggregate net income increased by a healthy percentage, spiking 199% to US$3.3 billion. This percentage increase didn’t match the steep growth rate of 2013, when net income soared by 462%. It was also heavily influenced by the US$1.6 billion breakup fee Shire received from AbbVie when the proposed merger between the two companies was called off in October 2014.

Research and development undertaken by the bioscience sector is particularly expensive. R&D tax credits are a valuable source of Government support for the sector not least because they stimulate innovation. Bioscience companies are often loss making in their R&D phase, therefore a tax credit is much more favourable than a corporation tax cut which is of no benefit to such companies because there are no profits against which to levy the tax.

Adjusting for this one-time event, European biotech companies actually added US$533 million in aggregate net income in 2014, an annual increase of 52%. This increase was driven largely by strong performances by Medivir, Actelion and Amarin, which each increased their net income by at least US$90 million. Indeed, only 45% of European biotechs boosted their net income in 2014, compared to 50% in 2013. Among those with sizeable drops in net income were Meda and Jazz Pharmaceuticals, while Alkermes reported a net loss. Meda’s net income fell as a result of one-time restructuring charges related to its Rottapharm acquisition, while the bottom lines of both Jazz and Alkermes were affected by the aforementioned increases in their R&D budgets.

The market capitalizations of European biotech companies increased strongly for the second straight year amid positive investor sentiment. Indeed, market caps of European companies actually increased seven percentage points more than those in the US in 2014. A catch-up phenomenon was at least partly responsible, given that European biotech market valuations didn’t increase as dramatically in 2013 as those of US biotechs, there was more room for a run-up in 2014. In all, 59% of European biotechs saw their market caps increase in 2014.

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Conference Date	June 19-20, 2017
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2nd International Conference on Bioscience June 19-20, 2017 London, UK

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